Pediatric Seizure (Actively Seizing and Febrile/Non-Febrile): Valid IV/IO Versed dose?

• A. 0.1 mg/kg IV/IO
• B. 0.2 mg/kg IV/IO
• C. 0.1 mg/kg IN/IM
• D. 0.5 mg/kg IV/IO

Answer: (A)

Midazolam given via IV or IO in an actively seizing child is dosed as 0.1 mg/kg. This amount delivers rapid seizure control while keeping the risk of respiratory depression lower than higher doses. A larger IV/IO dose, like 0.2 mg/kg or 0.5 mg/kg, increases the chance of oversedation and breathing problems. The 0.2 mg/kg figure is usually associated with intranasal administration, not IV/IO. If the seizure persists after the first dose, the protocol typically allows repeating once after a brief interval.