In pediatric hypoglycemia, what is the maximum dose of D10 that may be administered IV/IO?

• A. Oral Glucose: 15 g (> 2 y/o)
• B. D10: 5 ml/kg IV/IO (Max 100 ml)
• C. Glucagon: 0.5 mg IM (<20 kg) 1 mg IM (>20 kg)
• D. Zofran: 0.1 mg/kg IV/IO/PO

Answer: (B)

In pediatric hypoglycemia, the standard IV/IO dextrose bolus is 5 mL/kg of D10, with a maximum total of 100 mL. This provides about 0.5 g/kg of dextrose, delivering rapid correction while avoiding excessive fluid or glucose load. For example, a 20 kg child would receive 100 mL of D10. If IV access isn’t available, other routes or agents come into play, but the D10 dosing remains a 5 mL/kg bolus capped at 100 mL.